I want four kidneys.
Someone donate theirs to me. |
Having extra kidneys wouldn't do squat for hangovers though.
Of all the organs to have 4 of, kidneys are the most pointless. |
I always thought other parts of the body (such as the liver) processed the poisons which give you hangovers. Hmmmm.
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Thats right, all the kidneys do is filter out the wastes and produce urine.
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Kidneys can produce loads of urine if they need to, they are massively redundant with just 2. You can survive on 10% kidney function quite well.
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Aren't hangovers caused by dehydration? So having extra kidneys would do f*** all.
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hmm i mite get me a pair of those
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Hangovers come from dehydration and kidneys are used for the processing of fluids so I would assume that they can process water more efficiently and don't get dehydrated like everyone else.
If I had a couple of extra kidneys, I'd sell 'em. Better than living in fear of waking up in a bath tub full of ice with slash wounds down my sides. |
Dehydration is only one part of the hang over, another is the starvation of glycolysis intermediates.
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what causes the starvation? Because I know that if I drink only clear spirits I dont get a hangover at all or nearly as bad as if I have drunk wine or beer. I assume its due to the preservitives (read extra toxins) in beer and wine? nF please give scientific explanation of the starvation thing. Interested I am.
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Id rather have mega livers so that continued heavy drinking wouldnt result in liver failure :P Check this out then: In a study comparing the benefits of fatty acids in protecting against ethanol-induced liver damage, one group of animals was fed ethanol and tallow (saturated fat from animals) and a second group was fed ethanol and the unsaturated fatty acid linoleic acid. Results concluded that the animals fed tallow were protected from ethanol induced liver damage, whereas, animals fed linoleic acid d eveloped fatty liver necrosis and inflammation. A fatty maccas burger during a night of heavy drinking in the city is a good thing. :P |
In order to metabolise alcohol the body has to use metabolites from the glycolysis cycle, it also suppresses the activity of the cycle, which means that even if you have eaten the liver is struggling to produce the glucose.
Effectively you go hypoglycaemic (low blood sugar), when that happens your body thinks its in starvation and starts shutting things down it doesn't really need. It starts redirecting blood away from your digestive tract (and if necessary expelling whats there ... by vomiting :() to ensure that the brain and other critical organs get a steady supply. The bodies ability to maintain its body temperature gets a bit shaky, so you might drop half a degree or something. The reason you get dehydrated is obviously because you piss more, thats related to alcohol suppressing the reabsorbtion action of the kidneys. Caffiene works the same way. |
What's the point of drinking but not getting drunk? Kinda defeat the whole purpose really.
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I'm er.. guessing the cause of the fatigue is oxygen starvation to do with what you just said nef. A similar thing happens when you exercise and get a build up of lactate/lactic acid, but because a hangover is caused by a foreign element your body can't deal with it anywhere near as efficiently, especially seeing as it's been affecting your brain ;)
The best thing you can probably do is stimulate your psoas muscles with ice packs (on either side of your belly button down to your groin) which will accelerate the rate at which your body deals with it, as the psoas muscles are linked directly to the part of the nervous system which controls that stuff. If you were out having a run for example that would already be happening to some degree, but I don't think jogging with a hangover would be a very good idea. |
hangovers i can deal with, but this tropical ear infection is f*****g killing me
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I'm er.. guessing the cause of the fatigue is oxygen starvation to do with what you just said nef. How did you make that conclusion? |
At the very core of it, why else would organs be shutting down if they're not getting the blood they need - blood carries oxygen. Hypoglycaemia doesn't just reduce blood flow to the digestive tract, but other non-vital areas of the body as well.
I'd really love to hear another reason :P |
Tard, I'm not opposing what you said. I'm just showing a more defined end result to help explain my suggestion for treating it.
last edited by dais at 01:05:08 01/Mar/04 |
You spaz, read what i wrote. Oxygen has nothing to do with it. Organs need more than oxygen. You're clueless.
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I have years of first-hand experience with what you just wrote. Of course organs need more than oxygen, but quite obviously it's what provides their immediate nourishment.
But I forgot, cluey people call it your body "thinking it's in starvation". |
How did you make that conclusion?He used a jump to conclusions mat! You see you have this mat and you can JUMP to different conclusions. |
Thats a very bad idea. A horrible idea.
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If you had a clue you'd know that although Glycolysis is performed without oxygen its not performed in muscles due to lack of oxygen. You'd also know that telling someone whos hypoglaecemic to exercise is a truely stupid idea.
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Now who's not reading? To quote myself:
If you were out having a run for example that would already be happening to some degree, but I don't think jogging with a hangover would be a very good idea. Seriously nF, you just backed up what I said with your last post. I'm talking about oxygen starvation at a cellular level and there is a lot more to it than hypoglycaemia. Put the pieces together: when you exercise you breath more and the negative impact is lessened. When you drink your body is not in its aerobic cycle and the penalty is a hangover, with other factors affecting that. If you had a hangover and exercised that would make it worse because your body's aerobic cycle is not behaving efficiently, due to - you guessed it, oxygen starvation. Feel free to offer suggestions on how to deal with a hangover nef. |
So instead of drinking water before I go to bed to lessen my hangover in the morning, I should be putting on an oxygen mask?
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I would so sell two of em if I had 4 and get some phat cash.
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If you're not using oxygen effectively at a cellular level an oxygen mask won't do you much good.
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Your explanations sound like those of a HPE teacher.
Oxygen starvation can't really happen if you are breathing, oxygen levels aren't even one of the triggers to increase breathing rate. There is never really a lack of oxygen at a cellular level. As i said, the anerobic "cycle" for muscles is not related to oxygen levels at all. Thats a myth perpetuated by HPE teachers. The reason muscles use anerobic mechanisms is because they can act in a massively parrallel way, they can also react much much faster. And the ATP is generated in the cytoplasm rather than in the mitochondria where the aerobic processes happen. The lag time for aerobic respiration is something in the order of 30+ seconds (i've forgotten the exact number). |
Haven't really read any of the discussion, but a fella I went to school with found out he had 3 kidneys in year 11.
I'm pretty sure he had to end up selling at least one of them on the organ market to make up for his alco habbit, but he was still happy. Only the first and this sentence of this post are true. The second one is also true if you don't believe the third. |
I will take that as a compliment, see as I'm trying to explain it in a way other people can understand by giving real life examples.
If you go back and read your original post, then every one I've made following it I'm not disputing what you had to say originally. |
Just because what you say might seem logical doesn't mean its true.
Oxygen levels are not a trigger for respiration generally, despite the fact that i'd make logical sense. CO2 levels are far more important, as oxygen is generally in excess. Glycolysis (which is anerobic respiration) is activated in muscle cells in response to adrenaline, not low oxygen. And this actually makes logical sense, because if you have to run 100 metres you don't want to have to run 50 before you get any energy. |
In order to metabolise alcohol the body has to use metabolites from the glycolysis cycle, it also suppresses the activity of the cycle, which means that even if you have eaten the liver is struggling to produce the glucose. i give you 9.75 out of 10 for that explanantion - Shame about no apostrophe for "body's". :) I remember Dr Karl explaining it once, about causing a slight swelling of the brain causing pressure on a membrane around the skull which has pain receptors or smoe shiz. He also agreed that water was the best hangover retardant. I gotta admit ever since that I drink plenty of water after a big night out and have never had a drama - and I'm talking like after a whole bottle of bacardi. |
hangovers i can deal with, but this tropical ear infection is f*****g killing me Indeed . Ear Infections are s*** . So much pain |
Moving in to unchartered territory... the responsiveness of the blood vessels would be negatively affected by alcohol's influence on the brain/nervous system. That is what I've meant all along by oxygen starvation.
When your blood vessels dilate and blood pools, your body releases adrenalin - leading to the glycolosis as you said. And as for being at a cellular level, the cells aren't going to absorb what they need if the blood supply is deficient in some way. So thinking things through, you can see it's not at odds with what you're saying after all. That's why what I suggested should work, because you're stimulating that response and increasing the rate of glycolosis. At least I think so :P |
He really should think about becoming a donor :)
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The best way to avoid a hangover is to drink a huge amount of water before you goto bed.
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i'd say the best way to avoid a hangover is to not drink. but sifnt piss ups.
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I remember Dr Karl explaining it once, about causing a slight swelling of the brain causing pressure on a membrane around the skull which has pain receptors or smoe shiz. He also agreed that water was the best hangover retardant. Apparently starchy type foods before you start drinking can also help, because they'll up the amount of glycolysis intermediates. The problem is if you drink for an extended period of time. But yeah, definately water, and i know that one from personal experience. One thing i'd love to understand is why tap water tastes so bad when you are hung over. |
everything drunk Bosnians say is true.
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i dont like "doctor" karl overly
i reckon a lot of his info is sus last edited by Spook at 20:46:18 01/Mar/04 |
That just means you would be running to and from the toilet all night instead of getting drunk
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Apparently starchy type foods before you start drinking can also help, because they'll up the amount of glycolysis intermediates.I always thought it was because they absorbed the alcohol so it doesn't make it into your blood system. I know when ever I have a pasta meal or something similar before going out, it takes me a lot longer to get drunk. i dont like "doctor" karl overlyI remeber he told people to go out and do some experiment to do with TV tubes and lightning. He claimed it was totaly safe until an electrical safty guy rang up and said that if people performed that experiment then they would die. He didn't seem to like admitting that he was wrong. |
One thing i'd love to understand is why tap water tastes so bad when you are hung over. Yeh what is up with that?!? |
The only thing that taste good when you have a hang over is greasy food :) |
One thing i'd love to understand is why tap water tastes so bad when you are hung over. Since I smoke when I drink, anything bar soft drinks taste bad hung over (i like to call it ashtray mouth). Which brings me on to my second point, I always get a craving for coke with a hangover (or anything really sweet). Is this becuase of a low blood sugar level? |
i always crave orange juice when im hung over that s*** is the f*****g bomb
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Which brings me on to my second point, I always get a craving for coke with a hangover (or anything really sweet). Is this becuase of a low blood sugar level? Yeah i find that to a certain extent too. As for if its true, i have no idea. |